The Big Gamble: Hydroxychloroquine

[Doc]

4 hours ago, Deranged Rhino said:

 

But wait, what about all the people killed by HCQ?

[3rdnlng]

1 hour ago, Doc said:

 

But wait, what about all the people killed by HCQ?

This is the chart for that:

 

 

 

 

 

 

 

 

 

 

 

 

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[Deranged Rhino]

 

[Cinga]

Fauci Lied and People Died

 

https://www.americanthinker.com/blog/2020/08/bad_medicine_on_hcq_faucis_waterloo.html

 

Quote

 

Here in our country, Fauci continued to ignore the ever accumulating and remarkable early-use data on hydroxychloroquine and he became focused on a new antiviral compound named remdesivir. This was an experimental drug that had to be given intravenously every day for five days. It was never suitable for major widespread outpatient or at-home use as part of a national pandemic plan. We now know now that remdesivir has no effect on overall COVID patient mortality and it costs thousands of dollars per patient.  

Hydroxychloroquine, by contrast, costs 60 cents a tablet, it can be taken at home, it fits in with the national pandemic plan for respiratory viruses, and a course of therapy simply requires swallowing three tablets in the first 24 hours followed by one tablet every 12 hours for five days.

There are now 53 studies that show positive results of hydroxychloroquine in COVID infections. There are 14 global studies that show neutral or negative results — and 10 of them were of patients in very late stages of COVID-19, where no antiviral drug can be expected to have much effect. Of the remaining four studies, two come from the same University of Minnesota author. The other two are from the faulty Brazil paper, which should be retracted, and the fake Lancet paper, which was.

 

 

[Doc]

I figured that with the lack of news about remdesivir and my Gilead stock dropping, it was proving to be ineffective.  I wonder if Fauci has any stock in Gilead?

 

And the handling of HCQ has been nothing short of criminal.  Again an incredibly safe medication (when used properly) used by people billions of times over the past 60+ years without a single concern over its safety, which has a known mechanism of action (zinc ionophore) and which is cheap and easy to take,, gets smeared all because Trump promoted it.  It finally exposed the Dems, CHO and Lancet, not to mention Fauci, as the scumbags they are.

Edited August 15, 2020 by Doc

[BillStime]

34 minutes ago, Doc said:

I figured that with the lack of news about remdesivir and my Gilead stock dropping, it was proving to be ineffective.  I wonder if Fauci has any stock in Gilead?

 

And the handling of HCQ has been nothing short of criminal.  Again an incredibly safe medication (when used properly) used by people billions of times over the past 60+ years without a single concern over its safety, which has a known mechanism of action (zinc ionophore) and which is cheap and easy to take gets, smeared all because Trump promoted it.  It finally exposed the Dems, CHO and Lancet, not to mention Fauci, as the scumbags they are.

Idiots.

 

Follow the money

[B-Man]

 

BELIEVE IN SCIENCE: 

 

 There’s a Mountain of Evidence That Hydroxychloroquine Is an Effective Treatment for COVID-19.

 

 

 

 

[Doc]

1 hour ago, BillStime said:

Idiots.

 

Follow the money

 

Yup.  Gilead.

[B-Man]

 

 

TRUMP MUST BE STOPPED, NO MATTER THE COST: 

 

How Many Lives Will the Health Experts’™ Bizarre HCQ Disinformation Campaign Cost?

 

 

 

 

 

[Q-baby!]

5 minutes ago, B-Man said:

 

 

TRUMP MUST BE STOPPED, NO MATTER THE COST: 

 

How Many Lives Will the Health Experts’™ Bizarre HCQ Disinformation Campaign Cost?

 

 

 

 

 

None, we will be down to zero cases in no time. It will magically disappear! 

[Deranged Rhino]

How many other lives could be saved? 

 

[Doc]

1 hour ago, Deranged Rhino said:

How many other lives could be saved? 

 

 

The libs don't care.  The more lives lost and economic devastation, the better chance they have of ousting Trump.

[BillsFanNC]

It's impossible for any one person to keep on top of all the covid research being published so I tend to look to the review papers and drill down from there.  Here's a recent one that I found enlightening.

 

https://pubmed.ncbi.nlm.nih.gov/32793246/ 

 

"Mechanisms Underlying Potential Therapeutic Approaches for COVID-19"

 

A few excerpts for those interested in the real current state of HCQ research, and not nonsense spewed from media dolts and all too often repeated here.

 

Quote

In contrast, others have demonstrated that
HCQ has greater antiviral activity than CQ during SARS-CoV-
2 infection (18). Basically, CQ or HCQ exert their effects on
eukaryotic cells by increasing the vacuolar pH of organelles such
as endosomes and lysosomes. The increase in pH neutralizes
the acidic lysosomal pH, decreasing autophagosome-lysosome
fusion and autophagic degradation (59, 60). Autophagosomelysosome
fusion is essential for virus/cell fusion and immunemodulating
activity (61). CQ and HCQ can also modify the
glycosylation of ACE2, which binds to the spike protein S
of SARS-CoV. This may interfere with the virus-receptor
interaction (19). Additionally, an in vitro approach demonstrated
that CQ inhibits COVID-19 virus infection (62). Some studies
have indicated that HCQ also reduces the levels of some
proinflammatory cytokines, such as IL-6, IL-18, and TNF-a (63).
Indeed, CQ and HCQ inhibit endosomal TLRs and have antiinflammatory
effects by inhibiting prostaglandin synthesis or
lipid peroxidation (64).
Hence, it was suggested that CQ and HCQ represent a
potential new drug treatment for COVID-19. However, there are
some limitations in performing clinical trials in patients owing to
the restrictions on research studies using cell culture or animals
and side effects, such as cardiotoxicity and liver cytotoxicity,
due to the half-life of these compounds of ∼3.1 days (65).
However, the risk of toxicity in patients treated for 10 years
with HCQ for systemic lupus erythematosus was shown to be
approximately 7.5%and to be higher in patients treated for longer
periods (66). In COVID-19-associated acute infection, CQ and
HCQ are used for a very short time (∼5 days). Nevertheless,
acute adverse events, such as hypersensitivity and gastrointestinal
intolerance, require attention, especially in critically ill patients
who may develop similar clinical manifestations due to COVID-
19. Additionally, CQ and HCQ can be safely used during
pregnancy (67). Recently, a clinical trial with a small sample
size showed that HCQ treatment is associated with a decrease
in viral load in COVID-19 patients, and the effect is reinforced
by azithromycin (39). Because of the low number of patients
and the lack of some group controls during this recent study,
new national and international clinical trials are being conducted
to confirm the authenticity of these findings. A current clinical
trial of CQ and HCQ therapy in the treatment of COVID-19
in Europe may reveal new possibilities for antiviral therapy for
Frontiers in Immunology | www.frontiersin.org 5 July 2020 | Volume 11 | Article 1841
Benani and Ben Mkaddem COVID-19 Treatment
COVID-19 to stop the pandemic. Although the antiviral activity
of hydroxychloroquine remains uncertain, there have been
several controversies regarding the clinical benefits of this drug
in patients with COVID-19. Recently, a new publication showed
the beneficial effects of hydroxychloroquine or chloroquine when
used alone or with a macrolide on in-hospital outcomes for
COVID-19. Each of the drug regimens was associated with a
decrease in in-hospital survival and an increased frequency of
ventricular arrhythmias when used for the treatment of COVID-
19. However, this study was retracted from the Lancet journal
(https://doi.org/10.1016/S0140-6736(20)31174-0). In contrast,
an approved study by the Ethics Committee of Shanghai
Public Health Clinical Center under the number NCT04261517
demonstrated that the prognosis of COVID-19 patients with
moderate cases is good. However, a large sample size study is
needed to investigate the effects of HCQ in the treatment of
COVID-19 (68). A new study is ongoing and can be found
on ClinicalTrials.gov under the identifier NCT04303507 with
the official title “Chloroquine/Hydroxychloroquine Prevention
of Coronavirus Disease (COVID-19).” This study is a doubleblinded,
randomized, and placebo-controlled trial that will be
conducted in a healthcare setting. A total of 40,000 participants
will be recruited, and the investigators predict an average of 400–
800 participants per site at 50–100 sites. However, the estimated
completion date is April 2021.

 

 

 

[B-Man]

Trump Was Right All Along! Blocking COVID Cure HCQ Killed 10s of 1000s Say Latest Docs 

 

 

Last month, I reported on the thousands of doctors and scientists trying to cut through all the media gaslighting and make people understand just how deadly the pseudoscientific quack medicine Anthony Fauci’s been peddling really is.

 

Nobel Prize-winning biophysicist, Michael Levitt, has been sounding the alarm about our suicidal response to COVID-19 from the very beginning:

 

more at the link

 

 

[Tiberius]

6 minutes ago, B-Man said:

Trump Was Right All Along! Blocking COVID Cure HCQ Killed 10s of 1000s Say Latest Docs 

 

 

Last month, I reported on the thousands of doctors and scientists trying to cut through all the media gaslighting and make people understand just how deadly the pseudoscientific quack medicine Anthony Fauci’s been peddling really is.

 

Nobel Prize-winning biophysicist, Michael Levitt, has been sounding the alarm about our suicidal response to COVID-19 from the very beginning:

 

more at the link

 

 

You are such a tool. 

[B-Man]

10 minutes ago, B-Man said:

Nobel Prize-winning biophysicist, Michael Levitt, has been sounding the alarm about our suicidal response to COVID-19 from the very beginning:

 

3 minutes ago, Tiberius said:

You are such a tool. 

 

 

[CarpetCrawler]

43 minutes ago, B-Man said:

Trump Was Right All Along! Blocking COVID Cure HCQ Killed 10s of 1000s Say Latest Docs 

 

 

Last month, I reported on the thousands of doctors and scientists trying to cut through all the media gaslighting and make people understand just how deadly the pseudoscientific quack medicine Anthony Fauci’s been peddling really is.

 

Nobel Prize-winning biophysicist, Michael Levitt, has been sounding the alarm about our suicidal response to COVID-19 from the very beginning:

 

more at the link

 

 

 

Wow, great stuff in that link, thanks.

[Doc]

4 hours ago, B-Man said:

Trump Was Right All Along! Blocking COVID Cure HCQ Killed 10s of 1000s Say Latest Docs 

 

 

Last month, I reported on the thousands of doctors and scientists trying to cut through all the media gaslighting and make people understand just how deadly the pseudoscientific quack medicine Anthony Fauci’s been peddling really is.

 

Nobel Prize-winning biophysicist, Michael Levitt, has been sounding the alarm about our suicidal response to COVID-19 from the very beginning:

 

more at the link

 

The more dead people, the better it is for the libs.

[SectionC3]

4 minutes ago, Doc said:

 

The more dead people, the better it is for the libs.

 

Fake news.  I care about COVID casualties.  Unlike someone else, who believes simply that “it is what it is.”

[3rdnlng]

1 hour ago, SectionC3 said:

 

Fake news.  I care about COVID casualties.  Unlike someone else, who believes simply that “it is what it is.”

If you care so much about Covid victims then how could you be so cavalier about babies being pulled apart and dismembered right before they are to be born?