Jump to content

Recommended Posts

Posted
1 hour ago, GG said:

Still waiting for the spike in cases in Williamsburg Brooklyn after the funeral fiasco 2 weeks ago ….

 

Maybe the inward backwards sect is on to something?


Is it because the Jews have the cure ?

  • Haha (+1) 2
Posted
9 minutes ago, meazza said:


Is it because the Jews have the cure ?

 

It would only be fitting that the most primitive backward sect stumbled onto the cure.

  • Like (+1) 1
Posted

And...............they continue to lie. They outright come out and say the numbers are false. How much more do the sheep have to see? Or maybe they don't want to see. They are happy being obedient to big brother masters. I guess the safety (perceived) is a more palatable option to dangerous (again that's perceived) freedom?

 

Posted
39 minutes ago, GG said:

 

It would only be fitting that the most primitive backward sect stumbled onto the cure.

 

 

How are the Amish doing?

Posted (edited)
18 minutes ago, meazza said:

 

 

How are the Amish doing?

 

Good Q.   I don't know the population dispersion across PA counties.  Here's the PA map.  The case growth has slowed down in the last few days and is still centered around Philly & exurbs..  

Edited by GG
Posted
2 hours ago, plenzmd1 said:

Just had this done. Rite Aid parking lot in Colonial Heights VA.

 

Had an 11:30 slot, arrived right at 11:30, two lanes for testing, 1 car in front of me in each lane. Confirmed my ID,then wait for tent to open up.

 

The had a six foot folding table( perfect for slamming, but i digress), they stood at one end, sent a plastic tray with a swab and vial in it to car  window. Test consisted of opening the swab the swab, inserting in left nostril about halfway up, two full rotations in nostril..then hold there for 15 seconds.

 

Repeat for the right nostril. Seal in vial, put it back in tray, end of test.

 

Was there about 5 minutes, self administered, and was not what i feared which was that thing being shoved halfway down your nasal cavity.

 

Again , I have no inclination i have the virus, but if it takes more testing to get our lives back, i will do it.

 

 

how accurate can the test be if it is dependent on sticking it a certain distance up your nose

4 minutes ago, Magox said:

 

 

Get a load of this

 

 

 

 

 

European Virus?

 

rumor is that the strain in NY is similar opt he strain in Europe.

The Wuhan strain was tracked on in Oregon and west coast

 

The development of multiple distinct strains makes it almost impossible to ever develop an "effective" vaccine.

 

 

Posted
5 minutes ago, spartacus said:

how accurate can the test be if it is dependent on sticking it a certain distance up your nose

 

rumor is that the strain in NY is similar opt he strain in Europe.

The Wuhan strain was tracked on in Oregon and west coast

 

The development of multiple distinct strains makes it almost impossible to ever develop an "effective" vaccine.

 

 

 

I get that, but that isn't the point.

  • Like (+1) 1
Posted
7 hours ago, Reality Check said:

At this point in time, I find it a little odd that with so many people who have recovered from this, why there aren't more news stories interviewing these recovery stories. We could all use some positive stories about beating this disease, and yet there is almost nothing. I am sure it is nothing of course.

Remember the MSM adage:   If it bleeds it leads.

  • Like (+1) 1
Posted

Just wanted to post an update on my daughter Cassandra. First, she is doing fantastic. She is doing her school work, playing, and enjoying spending time with her family. It has been a week since we left Buffalo Children's Hospital. I want to thank all of you for the cards, kind words, and prayers. Many people have asked me what exactly happened so I will explain. I needed to collect my thoughts before I posted just because there is so much information.

Cassandra was diagnosed with myocarditis which is the inflammation of the heart. Only 1 out of 100,000 children have this happen and usually one of the causes is a virus. Cassandra happened to be the unlucky winner. The virus she contracted was called Coxsackie B3. This virus is a common childhood illness. Most young children have mild or no symptoms. Very few children are extremely sick and in Cassandra's case, she was literally struck by lightning being child 100,000. Overall, this condition is very rare for a common virus.

The day we took Cassandra to WCA ER in Jamestown is a day I will never forget. In the morning, Cassandra had a slight fever and seemed to be calm. The only alert I had was she pointed to her right side and stated that it hurt. Something in me and  alerted that perhaps she might have appendicitis and we rushed her to the emergency room. About ten minutes after she was admitted, Cassandra started to deteriorate while I and the health care professionals were watching. Immediately Buffalo Children's was called and a chopper flew in to stabilize her and send her out. Her hands and feet were getting cold and she was turning pale and blue. I couldn't believe what I was witnessing and that my child was dying in front of me. I also witnessed so much more which is too hard to explain at this time.

As Cassandra was being flown to Buffalo Children's Hospital, my husband and I drove. As we approached the city, the hospital contacted us by phone and asked for my consent to put her on life support. I told them to proceed but wasn't sure if she was going to make it. It was a critical time but we both had to stay focus to make it to where she was at. As we entered Buffalo Children's, both my husband and I were allowed to enter together just because security made an exception (COVID regulations) just in case she died and we were both there to say our goodbyes.

As hours passed, Cassandra was stabilized on ECMO life support. A kind doctor at Children's that night sat with my husband and I and stated we saved her life and that if we even waited an hour later, she would not be with us and if we would have rushed her to the hospital earlier, she may have been misdiagnosed and sent home. He mentioned the timing was perfect.

Cassandra's chances of surviving were less than 40% when she had to be put on life support (ECMO). In other words, miracles do happen and prayers are answered. It was a mere coincidence that Cassandra suffered this Coxsackie B virus during a COVID pandemic. As I am writing this, the best advice I could provide you is be careful. Careful I mean is wash your hands, cover your face, and respect distance. I am seeing people out there not doing this. What I learned from all of this is no one is an exception from getting any virus and it destroying them. It doesn't matter if your healthy or not. My daughter was extremely healthy before getting sick.

 

My sister posted few days ago. Glad doing well. Don't use facebook much.

 

Coxsackie B virus

 
 
 
 Share 
 
300px-Coxsackie_B4_virus.JPG
 
Coxsackie B4 virus.

Coxsackie B (also written coxsackievirus B) is a group of six types of enterovirus belonging to the Picornaviridae family. They cause symptoms ranging from gastrointestinal distress to aseptic meningitis, pericarditis and myocarditis. Like other enteroviruses, Coxsackie B viruses have a tropism for muscle cells and have been linked to myalgic encephalomyelitis and chronic fatigue syndrome, fibromyalgia,[1] as well as Type 1 Diabetes.

Symptoms[edit | edit source]

Symptoms of infection with viruses in the Coxsackie B grouping include fever, headache, sore throat, gastrointestinal distress, extreme fatigue as well as chest and muscle pain. It can also lead to spasms in arms and legs.

Types[edit | edit source]

Coxsackie B1[edit | edit source]

Coxsackie B2[edit | edit source]

Coxsackie B3[edit | edit source]

Coxsackie B3 is found in 20-25% of patients with cardiomyopathy and myocarditis.[2][3][4][5]

Coxsackie B4[edit | edit source]

Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells.[citation needed]

Coxsackie B5[edit | edit source]

Coxcackie B6[edit | edit source]

Immune system[edit | edit source]

In a mouse model of myocarditis, Coxsackievirus infection was found to upregulate Toll-like receptor 4 on mast cells and macrophages immediately following infection. It also increased numbers of mast cells.[6]

The induction of interferon signaling and the induction of apoptosis are required for normal control of a Coxsackie B3 infection. Coxsackievirus B3 cleaves Mitochondrial Antiviral Signaling (MAVS) protein and Toll/IL-1 receptor domain-containing adaptor inducing interferon-beta TRIF to inhibit type I interferon induction and evade host immunity.[7] Conversely, upregulation of MAVS inhibits Coxsackie B3 by increasing type-1 interferon production.[8]

Mitochondria[edit | edit source]

Coxsackievirus B3 cleaves Mitochondrial Antiviral Signaling (MAVS) protein to inhibit type I interferon induction.[9] Conversely, upregulation of MAVS inhibits coxsackie B3 by increasing type-1 interferon production.[10]

Exercise[edit | edit source]

Several studies of a mouse model of Coxsackie B3 myocarditis have found that exercise increases the virulence of the infection and results in poorer outcomes.[11][12][13][14][15] These studies compare two groups of mice, both infected with CVB3, one that is exercised and the other, sedentary. They found:

  • Exercised mice died of congestive heart failure (the majority while swimming) and had 530X the amount of virus.[14]
  • Exercised mice had increased viral titers, mortality and fiber necrosis.[12]
  • Exercised mice had higher viremia and virus in the hearts and no circulating interferon; non-exercised mice had detectable interferon activity, higher levels of neutralizing antibodies[15]
  • Exercised mice died at much higher rates (52% v. 0 sedentary mice), but not if they were immunosuppressed.[11]
  • Increased T cytotoxic, T suppressor, and T cytotoxic, suppressor/T helper cell ratio, and myocardial inflammatory and necrotic lesions with exercise at 48 hours after infection. "Failure to restrict physical activity in the acute phase of this infection may well contribute to the progression of the disease."[13]

Chronic infection[edit | edit source]

Main article: Non-cytolytic enterovirus
Coxsackievirus B is able to establish a chronic intracellular non-cytolytic infection which can persist for years. Non-cytolytic enterovirus infection does not involve the destruction of infected cells. Non-cytolytic infection is difficult to measure in the serum as viral particles remain in the cell walls of tissues.

The molecular mechanisms of non-cytolytic infection were examined in a small study comparing Coxsackie B2 virus cultured in vitro to RNA extracted via muscle biopsy from eight patients with a chronic fatigue syndrome diagnosis. All patients had symptoms of muscle fatiguability. Four of these samples tested positive for enteroviral RNA. In all four patients with enteroviral-specific RNA, the enteroviral RNA had equal amounts of positive sense and negative sense RNA. By contrast, CVB2 virus in culture produced positive sense RNA at a ratio of 100:1. An equal ratio of positive to negative sense RNA would inhibit the translation of virus-specific gene products, explaining the failure to attract a response from the host immune system, and my account for how CVB2 could establish a persistent infection in these four patients.[16]

Models of persistent infection of the heart[17] and brain[18] have also been studied in mice and in thyroid carcinoma.

In human disease[edit | edit source]

Viruses in the Coxsackie B family progress to myocarditis or pericarditis, which can result in permanent heart damage or death. Coxsackie B virus infection may also induce aseptic meningitis. As a group, they are the most common cause of unexpected sudden death, and may account for up to 50% of such cases.[19]

https://www.me-pedia.org/wiki/Coxsackie_B_virus

 

Coxsackie virus is crazy. See sudden death lots of people :( . 

 

If people think if a virus cannot attack the heart or place there think again. Or any place in human that a certain virus attacks.

 

  • Like (+1) 5
  • Awesome! (+1) 7
Posted

I was just thinking, if Cuomo is calling this virus the "European virus" and considering that 65% of the Virus in the US researchers estimate came from New York.

 

By his logic, we may as well begin calling it the New York Virus.   Amirite?

  • Like (+1) 6
  • Awesome! (+1) 1
  • Thank you (+1) 1
Posted
1 hour ago, spartacus said:

 

The development of multiple distinct strains makes it almost impossible to ever develop an "effective" vaccine.

 

 

I just don't want to let this fear-spreading statement stand. That's not true unless the vaccine developed attacks something in one strain that is much different than another. Most of the vaccines so far have been focused on the spike part of the virus, which is largely unchanged between strains. 

  • Awesome! (+1) 1
Posted
4 minutes ago, Magox said:

I was just thinking, if Cuomo is calling this virus the "European virus" and considering that 65% of the Virus in the US researchers estimate came from New York.

 

By his logic, we may as well begin calling it the New York Virus.   Amirite?

 

 

 

 

 

 

giphy.gif

  • Like (+1) 1
  • Haha (+1) 1
Posted
1 hour ago, GG said:

 

Good Q.   I don't know the population dispersion across PA counties.  Here's the PA map.  The case growth has slowed down in the last few days and is still centered around Philly & exurbs..  

 

I don't know how they are doing medically, but I can tell you from experience, they and the Mennonites *hate* wearing the masks, washing hands and being told only one of them is permitted in a store.  They are slowly getting with the program.  Slowly.    

Posted

 

4 hours ago, Rob's House said:

 

I do believe that masks reduce the spread of the virus, but if the border wall debate taught me anything it's that any measure that isn't 100% effective isn't worth doing at all, so I won't be using a mask.

 

Makes sense.  Rather than bother with limited effectiveness, just go straight to no effectiveness.  Seems like a solid plan. 

  • Like (+1) 1
  • Haha (+1) 1
Posted
4 hours ago, Rob's House said:

 

I do believe that masks reduce the spread of the virus, but if the border wall debate taught me anything it's that any measure that isn't 100% effective isn't worth doing at all, so I won't be using a mask.

 

You make a good point. :lol:

  • Like (+1) 1
×
×
  • Create New...