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Matchup to Watch: Colts' Anthony Castonzo vs. Buffalo's Jerry Hughes

 

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Jerry Hughes never developed in the Colts defense. He was introduced by Colts coach Jim Caldwell and President Bill Polian at the Colts Complex on April 23, 2010. (Photo: Sam Riche/IndyStar)

 

A first-round pick who has lived up to expectations in Indianapolis will spend most of his Sunday trying to stop a first-round pick who had to leave the Colts to find success in the NFL.

 

Bills defensive end Jerry Hughes and Colts left tackle Anthony Castonzo were Bill Polian’s final two first-round picks, players who were supposed to serve as building blocks on the line of scrimmage as the Colts retooled around Peyton Manning.

 

Castonzo has been rock-solid since the day he arrived in Indianapolis. Hughes, on the other hand, seemed like a perfect fit to follow in Robert Mathis and Dwight Freeney’s footsteps, but he had to be traded to Buffalo after three seasons to blossom into a difference-making pass rusher in the NFL.

 

This will be the fifth time Hughes has played against the Colts since the trade, but the first time he’s returned to Indianapolis for a regular-season game. Hughes returned to Lucas Oil for his first preseason game as a Bill in 2013, but a 12-snap appearance in the preseason is a world apart from taking the field against the Colts in mid-October.

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