Know anyone with a disease? Read this

[Security]

Alcohol and pot are NOT the same. I like both. Your rarely get a little high. I can have a few beers. 2-3, just like the taste with dinner. No buzz. You take one or 2 hits, you are stoned. There is no just a little, you are stoned.

[Deranged Rhino]

Alcohol and pot are NOT the same. I like both. Your rarely get a little high. I can have a few beers. 2-3, just like the taste with dinner. No buzz. You take one or 2 hits, you are stoned. There is no just a little, you are stoned.

 

That just mean you aren't smoking enough.

 

I can get "a little" high as easily as I can catch a buzz off a few cocktails or adult beverages.

 

... And now comes the part where I take stock of my life choices as I realize what I just wrote...

[bbb]

My experience was always like Security said. I was either flat out stoned or nothing. There was never a little stoned for me.

[Security]

http://news.yahoo.com/heavy-pot-teen-years-may-predict-later-life-183940372.html

 

heavy pot use means you are more likely to be on disability. I bet this is actually that you are just a lazy piece of crap. Study cannot prove pot, or anything really causes disabilities, but still, pot is not good for most people.

[Bob in Mich]

Cannabis finds its way into treatment of Crohn’s disease

 

http://www.ncbi.nlm....pubmed/24356243

 

From the report

 

In ancient medicine, Cannabis has been widely used to cure disturbances and inflammation of the bowel. A recent clinical study now shows that the medicinal plant Cannabis sativa has kept its expectancies proving to be highly efficient in cases of inflammatory bowel diseases (IBD).

 

In a prospective placebo-controled study, Naftali and coworkers (Clin. Gastroenterol. Hepatol. 11,1276-1280. e1., 2013) have shown what has been largely anticipated from anectodal reports, that Cannabis produces significant clinical benefits in patients with Crohn’s disease. The mechanisms involved are not clear yet but most likely include peripheral actions on cannabinoid receptors 1 and 2, and may also include central actions.

 

There is also this report that I mentioned in an earlier thread

 

http://www.ncbi.nlm.nih.gov/pubmed/23648372

Edited August 20, 2014 by Bob in Mich

[Bob in Mich]

Cannabinoids as therapeutic agents in cancer: current status and future implications

Published: July 17, 2014

 

http://www.impactjou...233&path[]=3664

 

From the report

 

Conclusions and future directions

Cannabinoids exert a direct anti-proliferative effect on tumors of different origin. They have been shown to be anti-migratory and anti-invasive and inhibit MMPs which in turn degrade the extra-cellular matrix (ECM), thus affecting metastasis of cancer to the distant organs. Also, cannabinoids modulate other major processes in our body like energy metabolism, inflammation, etc.

 

These data are derived not only from cell culture systems but also from more complex and clinically relevant animal models. Before cannabinoids could be used in clinical trials, there is need to explore more knowledge on several issues such as anti-tumorigenic and anti-metastatic mechanisms as well as which type of cancer patient populations would be more responsive for cannabinoid based therapies.

 

Data presented in this review suggest that cannabinoids derived from different sources regulate differently signaling pathways, modulate different tumor cell types and host physiological system. It is important to understand which of the cannabinoid receptors are expressed and activated in different tumors as each receptor follows a different signaling mechanism

 

------------------------------

And, from the GW Pharmaceutical website http://gwpharm.com/oncology.aspx

Info: Cannabinoids in Oncology

 

The possibility that cannabinoids, including endocannabinoids, may treat cancer is supported by an ever increasing body of available evidence. In simple terms, cancer occurs because cells become immortalised; they fail to heed customary signals to turn off growth. A normal function of remodelling in the body requires that cells die on cue. This is called apoptosis, or programmed cell death and this process fails to proceed normally after malignant transformation. As will be discussed in greater detail below, THC, CBD, and perhaps other phytocannabinoids promote the re-emergence of apoptosis so that certain cancer cell types will in fact heed the signals, stop dividing, and die

 

 

This report from the National Cancer Institute is interesting too

 

http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4#Section_26

 

From the report

 

Cannabinoids may cause anti-tumor effects by various mechanisms, including induction of cell death, inhibition of cell growth, and inhibition of tumor angiogenesis invasion and metastasis Two reviews summarize the molecular mechanisms of action of cannabinoids as antitumor agents. Cannabinoids appear to kill tumor cells but do not affect their nontransformed counterparts and may even protect them from cell death.

Edited August 24, 2014 by Bob in Mich

[FireChan]

I respect Bob's hustle.

[Security]

http://www.caintv.com/seven-ways-pot-legalization-ha

1. The majority of DUI drug arrests involve marijuana and 25 to 40 percent were marijuana alone.

2. In 2012, 10.47 percent of Colorado youth ages 12 to 17 were considered current marijuana users compared to 7.55 percent nationally. Colorado ranked fourth in the nation, and was 39 percent higher than the national average.

3. Drug-related student suspensions/expulsions increased 32 percent from school years 2008-09 through 2012-13, the vast majority were for marijuana violations.

4. In 2012, 26.81 percent of college age students were considered current marijuana users compared to 18.89 percent nationally, which ranks Colorado third in the nation and 42 percent above the national average.

5. In 2013, 48.4 percent of Denver adult arrestees tested positive for marijuana, which is a 16 percent increase from 2008.

6. From 2011 through 2013 there was a 57 percent increase in marijuana-related emergency room visits.

7. Hospitalizations related to marijuana has increased 82 percent since 2008.

Legal marijuana means more people smoking marijuana (especially kids), which means more problems in the realms of crime, public health, driving hazards, school discipline. One of the most idiotic arguments in favor of pot legalization is that it "takes the crime out of it." It does no such thing. It creates so much undisciplined behavior on the part of people who are not the sharpest tools in the drawer to begin with, the result is far more overall criminal behavior, even if possession of pot itself is not something to be prosecuted.

About that: If legalization is not supposed to lead to a rise in teens smoking pot, then how do you explain drug-related suspensions and expulsions up 32 percent in four years? Because it obviously does lead to more teens doing it. There is no way it could be otherwise. Any time you remove the sanction from a behavior, you get more of that behavior. More adults able to acquire pot legally means more people for teens to get it from. Come on. Don't be a moron. Use your brain for once, if you still have any of it left.

And stop with the idiocy about how "the war on drugs failed" because it didn't result in fewer people doing drugs. Name one other criminal law that's judged in that way. Rapists are still at it. Anti-rape laws have failed!

Are you really that stupid? The purpose of a criminal law is to impose a sanction on those who commit the crime, and to protect society from those same people.

If more people are using drugs, the law hasn't failed. Those people have failed. And now we're seeing some of the social costs of changing the law to accommodate their failures.

[Bob in Mich]

This topic seemed like a good one after yesterday's Bills-Bucs game. It discusses both anxiety and depression. I know, I know, it is only the preseason

 

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

 

Published 5-Dec-2012

 

http://www.ncbi.nlm....les/PMC3481531/

 

From the Report's Abstract Section

 

Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It lacks the psychotomimetic and other psychotropic effects that the main plant compound Δ⁹-tetrahydrocannabinol (THC) being able, on the contrary, to antagonize these effects. This property, together with its safety profile, was an initial stimulus for the investigation of CBD pharmacological properties.

 

It is now clear that CBD has therapeutic potential over a wide range of non-psychiatric and psychiatric disorders such as anxiety, depression and psychosis.

 

 

GW Pharmaceuticals is also investigating the use of cannabinoids for mental disorders.

 

http://gwpharm.com/p...conditions.aspx

 

On the basis of laboratory evidence, anxiety and depression are promising targets for cannabinoid medicines and there are some preliminary human data in support of this^i,ii. Emerging evidence suggests that the cannabinoid, cannabidiol (CBD), possibly in combination with other cannabinoids, may have potential utility in schizophrenia not only as an anti-psychotic, but also in the alleviation of the metabolic and inflammatory abnormalities associated with the disease.

 

CB1 antagonists may have a role in relapse-prevention in the treatment of addictionⁱⁱⁱ. Other possible targets for the future based on human anecdote or limited laboratory research include bipolar affective disorder, post-traumatic stress syndrome, eating disorders, and insomnia

[bbb]

So something that is the trigger for anxiety, psychosis, etc. is now going to cure those things??

 

Sounds like Homer Simpson's description of beer.

[Bob in Mich]

bbb, cannabis contains about 100 cannabinoids in varying proportions depending on the strain.

 

One of them, THC, can make things worse for the psychotic person. One cannabinoid, CBD, can help calm that same person.

 

Depending on the ratio of these compounds found in an individual strain, a high THC strain could trigger an anxiety attack where another strain, one high in CBD, could bring someone down from an anxiety attack.

[bbb]

Why not just take the CBD without the THC?

[Bob in Mich]

For some conditions, a high CBD strain is just the ticket.

 

For some other conditions though, the THC is apparently the key to the effectiveness of the cannabis. In my opinion, many of the cannabinoids offer hope of medicinal properties. There just needs to be more research.

 

http://www.cureyouro...cers-cells.html

 

Study Finds Cannabinoids Can Kill Gastric Cancer Cells

 

from the article

 

This study published in both journals offers hope in treating gastric cancers with cannabis. The researchers in Korea have discovered that WIN 55,212-2, a synthetic version of the cannabinoid THC that is found in cannabis, is antineoplastic. That means it can inhibit and prevent the growth and development of malignant gastric cancer cells.

Edited August 25, 2014 by Bob in Mich

[bbb]

All this and it makes great rope. Amazing.

[ExiledInIllinois]

All this and it makes great rope. Amazing.

 

It makes better than cotton shirts too!

 

http://www.collective-evolution.com/2013/07/17/hemp-vs-cotton-the-ultimate-showdown/

 

Comfort & Longevity

 

Cotton: Generally very comfortable to begin with, as you continue to wear cotton it ‘breaks in’ to become even more comfortable. There is no denying how soft cotton can be, but it is also true that cotton fibres break down over time and the more it is washed the faster it breaks down.

Hemp: The hemp fibre used in clothing is a strong natural fibre that, like cotton, gets progressively softer with each passing day you wear it and each time you wash it. Although it may not start off quite as soft, it is still soft and certainly would not be considered uncomfortable. The plus is that the fibre is much stronger and durable. Repeated washed will not break the fibre down anywhere near as quickly as cotton. Creating more hemp clothing would mean we would need to produce much less clothing.

The victor: Hemp

[4merper4mer]

 

Hemp: The hemp fibre used in clothing is a strong natural fibre that, like cotton, gets progressively softer with each passing day you wear it and each time you wash it. Although it may not start off quite as soft, it is still soft and certainly would not be considered uncomfortable.

 

Translation: Scratchy nipples.

 

Anyway let's get this thread back on track. Bob knows a little already but my tied for fifth cousin Brenda is sick with something strange. It started with nausea and sometimes puking. I know everyone gets sick sometimes but not Brenda. Anyway it kept happening to her. It wasn't just a few days, but it wasn't every day. It would seem to go away and then it would come back. Then it pretty much stopped but other weird stuff started to happen. Some of it really weird.

 

Can pot help?

[Bob in Mich]

Please just give us the punchline already or stop with this lame pregnant cousin Brenda tale. This is your 4th try at getting someone to bite.

[4merper4mer]

Please just give us the punchline already or stop with this lame pregnant cousin Brenda tale. This is your 4th try at getting someone to bite.

 

You sound like a pusher. Pot cures everything but you won't answer anything. Just list every disease known to man and say that pot cures it. How much per click are you getting paid?

[Bob in Mich]

This is my understanding of how it can be effective on so many illnesses.

 

(Recall that I am not a medical professional )

 

The reason it works on so many diseases is that cannabinoids are similar to our body's own endocannabinoid molecules which are used to regulate very many bodily processes. The endocannabinoids are used to communicate between many different cell types in our bodies. Cannabinoid receptors are found in nearly every organ in the body

 

When we are healthy, we can self regulate imbalances that happen in our bodies. We are designed to do just that. Endocannabinoids, as it turns out, are one of the messenger molecules used by our body to self regulate. This includes things like blood pressure, blood sugar, inflammation response, nerve signals, and more. Cannabinoids often provide a feedback signal in the messaging process

 

Consider that if the body is lacking in messenger molecules, the natural re-balancing signals do not get through and so the body does not bring itself back into balance.

 

We can, in some cases, provide plant molecules that so closely resemble our own endocannabinoids that these are able to function as the messengers. Once the signals are restored, the body again self regulates and brings itself back into balance.

Edited August 29, 2014 by Bob in Mich

[Rob's House]

http://www.caintv.com/seven-ways-pot-legalization-ha

1. The majority of DUI drug arrests involve marijuana and 25 to 40 percent were marijuana alone.

2. In 2012, 10.47 percent of Colorado youth ages 12 to 17 were considered current marijuana users compared to 7.55 percent nationally. Colorado ranked fourth in the nation, and was 39 percent higher than the national average.

3. Drug-related student suspensions/expulsions increased 32 percent from school years 2008-09 through 2012-13, the vast majority were for marijuana violations.

4. In 2012, 26.81 percent of college age students were considered current marijuana users compared to 18.89 percent nationally, which ranks Colorado third in the nation and 42 percent above the national average.

5. In 2013, 48.4 percent of Denver adult arrestees tested positive for marijuana, which is a 16 percent increase from 2008.

6. From 2011 through 2013 there was a 57 percent increase in marijuana-related emergency room visits.

7. Hospitalizations related to marijuana has increased 82 percent since 2008.

Legal marijuana means more people smoking marijuana (especially kids), which means more problems in the realms of crime, public health, driving hazards, school discipline. One of the most idiotic arguments in favor of pot legalization is that it "takes the crime out of it." It does no such thing. It creates so much undisciplined behavior on the part of people who are not the sharpest tools in the drawer to begin with, the result is far more overall criminal behavior, even if possession of pot itself is not something to be prosecuted.

About that: If legalization is not supposed to lead to a rise in teens smoking pot, then how do you explain drug-related suspensions and expulsions up 32 percent in four years? Because it obviously does lead to more teens doing it. There is no way it could be otherwise. Any time you remove the sanction from a behavior, you get more of that behavior. More adults able to acquire pot legally means more people for teens to get it from. Come on. Don't be a moron. Use your brain for once, if you still have any of it left.

And stop with the idiocy about how "the war on drugs failed" because it didn't result in fewer people doing drugs. Name one other criminal law that's judged in that way. Rapists are still at it. Anti-rape laws have failed!

Are you really that stupid? The purpose of a criminal law is to impose a sanction on those who commit the crime, and to protect society from those same people.

If more people are using drugs, the law hasn't failed. Those people have failed. And now we're seeing some of the social costs of changing the law to accommodate their failures.

 

No matter how hard I try I just can't get worried about it.