As you alluded, Mel is pretty much never correct, so I wouldn't worry too much about that.
It is possible that 4 QB's go in the first 5 picks though, in which case I think we stay put and take a dominant LB at 12, then 22 leaves plenty of options (including QB, dependent on how high they are on Jackson or Rudolph).
There's also the option of waiting until next year, and maybe even dealing 22 for a first next year, if you're really not sold on the guys left. I definitely don't want them just reaching on a guy to appease the fan base. The key isn't getting A guy, it's getting THE guy.