Well, looking at it from the opposite view, UB's Naman Roosevelt played briefly for the Bills over 2 seasons after being promoted from the practice squad, but after he was cut in the final cutdown if 2012, didn't make another NFL roster. He went to the CFL and has had a solid career there, making the divisional All Star team in 2017.
So, a bottom of an NFL roster player is a solid starter in the CFL. This of course does not take into account the improvements in his play while in the CFL.