AZ might be really bad this year, but if they can get Williams and Harrison, they could turn it around in a hurry, especially if Paris Johnson turns out to be a solid LT and they hit on a couple of defenders in the draft.
And yes, I think there is every indication that the Lambs will shut down both Kupp and Stafford this year, at which point you can expect Aaron Donald to take a few "veteran rest" weeks, or maybe even get traded...