We've had seasons since 1977. Used to sit at the 35 yard line, 20 rows up on the home side -- good seats, but the perspective gets really skewed when the teams were at the other end of the field.
When the stadium was renovated we actually got bumped further out and down to the 25 yard line, 13 rows up (Section 132). I was not happy, but still pretty good seats. I later upgraded and moved up in the same section to row 33, near the top of the section, and now in the middle of the section near the 30 yard line. Much better view, I think, although I miss being closer to the Bills bench.
Home side is definitely better because of the sun issue as well.
Inherited the seats from my dad, though, so I can't tell you how long it would take to get there (or further in).