Tony, Tony, Tony. Last season was merely setting the table for this season.
Personally i think Tony is going to be killed or accidently die. There are a number of ways this could happen. The skin cancer, mob war, the bear in the back yard, etc. But i think after he dies he returns to that house that he visited after Uncle June shot him and lets go of the briefcase. Inside, he sees Adrianna and all those that he has had a hand in killing. Curtain drops, shows over.