Now that the Bills are rolling, EVERYONE is going to bring their "A" game, for their own reasons. I expect Cleveland-Pittsburgh to play above their means, just because. Pitt and Cincy because they need the win, Browns and 49'ers because it's a "respect" game and they can concentrate more effort to a single game, should they want to.
There is always the ever present threat of bird flu, plague and nuclear holocaust to deal with as well.
One game, heck one quarter at a time. Buffalo not only has to run the table, but they have to do it without anyone else getting hurt against some teams that just might be hungry.
I think they could do it. But it won't be easy.