Seattle over NO. I think the Saints will keep it close this time, but Seattle will just pull away in the second half.
I really don't want to pick them, but I can't see New England losing at home. Indy escaped last week...they won't this week.
I'd like to see Carolina win, but I think San Fran is just too tough. Kaepernick will win it with his legs and they'll figure out how to contain Cam Newton.
Denver has been waiting for a year and won't lose this one. San Diego is good and on a roll, but I think Manning will do everything in his power and Denver's D will step up.