Nicolino is the loss IMHO, but it is not even a big one. d'Arnaud, Gose, Syndergaard, Aaron Sanchez, Roberto Osuna, Danny Norris...all staying in Toronto. Hechhavarria is all glove, no bat (think Rey Ordonez bad with the bat). Marisnick is raw and overrated. DeSclafani is already 23 and striking out 6 batter per nine in the low minors. I mean...to not even get an everyday piece like d'Arnaud to build around is shameful for FLA (but the whole thing is shameful for FLA).
As for Escobar...he has been drummed out of two organizations for his bad attitude (ATL and TOR) and FLA says they may flip him. He is a marginal player at best.