RU5781
-
Posts
269 -
Joined
-
Last visited
Content Type
Gallery
Profiles
Forums
Events
Posts posted by RU5781
-
-
Whatever.
I hate to break it to you, but the Smiths are one of the most influential bands in the history of music.
-
Damn. I was kind of interested in hearing what exactly it is you do.
Haha. It's nothing too exciting. I work with the sites, the CRA's, and data.
-
Very interesting, JC. I hadn't heard of this. i will certainly check it out and keep my eye on this one. Thanks
I've found a pretty effective pain management system for my brother and myself. Fentaynal patch supplemented with gabapentin (or Lyrica). My bro is pretty much addicted to pain pills, but this treatment has allowed him to cut back on the pills quite a bit. As he is a dialysis patient, he can't use a high dosage of fentaynal, If he could, I'm guessing he could drop the pills almost entirely.
I know they don't work for everyone, but for those they help, I think fentaynal patches are a freakin' wonder drug.
Gabapentin is Neurontin, Pregabalin is Lyrica.
Lyrica frightens me more than Neurontin. Lyrica can cause significant weight gain, and could be a B word for diabetes. Also, it is addictive.
Neurontin has been around much longer, but eventually you become tolerant to it.
Fentanyl is good, but STRONG! Has he tried Lidoderm for specific site pain?
The FDA is dragging its heels on Acomplia, and I'm not quite sure why (the data doesn't support the holdback). I believe Merck and Pfizer are also working on something very very similar. It's going to be an entire new class of drugs, and they think they have only scartched the surface (I'm sure Coli, NG, and Mr. Info know a lot more on this than me).
-
If you can wait that long, that should be more than adequate time to make that assessment. A lot of people are unable to wait that long. For example, I know some people who are having a difficult time managing pain since Vioxx was withdrawn. They have tried other analgesics but they have not been as effective. These people would be willing to accept the risk associated with Vioxx for the pain relief. However, if a similar analoque to Vioxx was released, they would probably try it right away to see if it was effective for them. Of course, the assumption is that this is all being performed and monitored under the care of a personal physician. And, no, I do not work for Merck.
There is a drug from Sanofi-Aventis awaiting approval called Acomplia (it probably won't be marketed under that name).
They are expecting sales to be around 12 BILLION in its first year.
The drug deals with the endo-cabbinoid (sp?) section of the brain (the first of its kind). It was originally developed to help people stop smoking marijuana. What they found out was, it stops addiction (alcohol, food, drugs, smoking), lowers your blood pressure, lowers your cholesterol, and raises your good cholesterol.
Practically everyone is going to jump on this drug (myself probably included). Sanofi better hope and pray that there are no serious events associated with this drug, or they're done.
The only documented side ffects are it could cause/increase depression, and could raise anxiety is a small portion of people.
Disclaimer: I don't work for Sanofi-Aventis. I read about this is Reader's Digest a few years ago (when it was being developed) and have follwed it ever since.
-
Could you elucidate a bit more? That can mean several things: a physician monitoring clinical compendium as they are submitted, someone studying the stability data, you could be dealing with suppliers, manufacturing, packaging, and labeling. The marketing staff is involved in analyzing this data. You could even be in IT, managing the databases/security where this data is located, or perhaps in QA/QC or compliance. End stage development could mean any number of things. If it is not obvious, I work for a pharmaceutical company. Actually, I have worked for several in both R&D and manufacturing. And, yes, I have some open positions...good analytical scientists, microbiologists, and formulators.
Check your PM.
-
Morrissey is one of the greats of our time. I saw him a few years ago in Philly, and he's playing at The Mann Center in Philly in June.
-
OH...YOU'RE the guy who skews the data.
Got it!
Haha, there is no skewing whatsoever. The FDA watches like a hawk, and if they suspect ANYTHING fishy went on (anything, to the point if they even suspected we randomized the patients incorrectly), the fines are astronomical.
-
Curious - what is your position in the company? Are you a Sr. Scientist, work in IT, Marketing, HR, etc.? There are many people who work in a pharmaceutical organization that do not have a good understanding of the development, pre- and post-market work (clinical studies, stability, etc.) that is involved.
I work in LSDS (Late Stage Development Services) dealing with Phases III and IV of the Clinical trial.
-
The moral of the story is...when a new drug comes out, wait a few years before taking it.
Zelnorm was approved in July of 2002.
It had gone through Clinical Trials before that, so you're talking at least 7-8 years of data on the drug.
-
thats my neck of the woods. As we say- scalp them!
I've always wanted to go there Pete. How is it?
-
I don't have a link (I'm sure it's all over the internet) put today the FDA put pressure on Novartis to recall Zelnorm.
They found that the drug causes a higher incidence of stroke and heart attacks, and can also lead to heart valve problems.
I work for a drug company and this was all over today.
-
Yeah, they choked all over the fuggin' ice last year.
And this game wasn't important at all. Brodeur looked like shiit.
Marty played a crappy game. Big deal. I'd take him over Miller in a big game any day of the week.
-
Who's crying now?
Who's crying Jimmy?
We all know come playoff time, the Sabres CHOKE!
-
dude, i hate to be one who complains. but how can the Devils crosscheck Briere 3 times and we get a penalty??
Wahhhhhhhhhhh!!
-
This is my son in whome I am well pleased.
My father needs to take a spelling class.
-
I saw it yesterday. I thought it was great as well.
-
What does it mean to "underming"?
-
Crayonz and Ed making sense?
Hey, don't lump me in with our NJSue wannabe.
Anyway, thank you for all of your warm wishes. The ceremony was beautiful, and the reception was so much fun.
-
You need to get laid, Ed.
And I'm only saying this because: you're a friggin' newlywed, and you're posting on the PPP board. Why aren't you on your !@#$ing honeymoon????? Walk away from the computer, and go bang your new bride.
Haha, we're not going on our official honeymoon until December (she just started teaching college, and wasn't allowed to cancel class for more than two days. Plus, I start a new job on monday, soooo...)
We've been banging since like the second week in our relationship, so it's not like it's a "new" thing.
-
Okay, maybe "retards" was a little harsh...but Jesus Christ...
You rang?
-
I heard that the chocolate shortage was due to global warming melting it all away. Don't believe me? Well it's impossible to find Snow Caps at a movie theater anymore.
-
Why aren't you staying away to make people think you are actually Ed and on your honeymoon?
-
I had to try it myself and you're right!
It's just a sample.
Once you submit you rpics, it's voted on, and you get accepted, then everything changes.
I have a friend who is on there.
-
For goodness sake stop it. ( oh , by the way good for you on wedding
) I really thought Cammy won the fight (mainly because Belak didn't want to fight anymore and gave up).Thanks for the nice wishes! Do you live in Toronto (my wife used to live there and had seasons for the Leafs)?
I want to make it up there at some point and see a game.
Wouldn't want to work in New Jersey...
in Off the Wall Archives
Posted
I'm shocked!
I did hear today though that Lamoriello felt the team wasn't focused or prepared.