Well I hate to do this, but I think this game is a tough spot for the Bills: Miami coming off a loss, Miami is great at home in September, and with the Bills starting 4 rookies on defense, I think there will be some more growing pains on Sunday.
However, I think the Bills will show more positive signs that the team is heading in the right direction. JP will have his moments. Now if Willis can have a big game, and the Bills can stay away from turnovers again, they will have a chance.
Another thing: If you split up the at New England and at Miami games during the season, you would probably say those are two losses. It is just harder to take when they are back-to-back and the first 2 games of the season. But do not fret fellow Bills fans: Rosier days are ahead.
Prediction: Miami 27, Buffalo 17
Yours?