From August 1950 through August 1961, teams from the NFL and CFL played six times during the NFL preseason, in Canada. (For the Canadian teams, the games were exhibitions played during the CFL regular season.)
It started in 1950, when the Giants beat the Rough Riders in Ottawa, 27-6. The following year, the Giants thumped the same team in the same town, 41-18.
The series resumed eight years later, when the Chicago Cardinals clobbered the Argonauts, 55-26, in Toronto. In 1960, the Steelers slammed the Argonauts in Toronto, 43-16.
The exercise ended the following year, with a pair of contests played three days apart. On August 2 in Toronto, the Cardinals (which had since moved to St. Louis) cold-cocked the Argonauts, 36-7. On August 5, the Bears bested the Alouettes in Montreal, 34-16.
But the Canadians saved a little face three days after that. In the one and only AFL-CFL game, the Tiger-Cats took apart the Buffalo Bills in Hamilton, 38-21.