The problem i see going forward with the bills is balance 16 runs with RB's and 51 passes. Not every team is going to be able to exploit the bills. Teams with a good pass rush that can pin their ears back and just rush all game because the bills run so little are going to be a problem.
Teams can basically dare the bills to run or not even scheme or worry about it. The Steelers who normally blitz a ton seen that they could get pressure with just 4, its the same thing that happened to the chiefs in the super bowl.