You are missing a major point in this discussion, if Kincaid is off the field, a WR will get more targets. I think the Bills offense is better when the one TE on field can both block and catch a few balls. Kincaid is so one dimensional that you are better off playing a WR instead of a one-dimensional TE. That is just my opinion, and the way I like to see football played. I think the Bills best offenses was with 3 WR, 1 RB and 1 TE on field. Knox was able to contribute more in the passing game, because the WR now in the slot was creating much more space than Kincaid is.
In an entirely healthy lineup, I would rather see Cook, Cooper, Shakir, Knox, Coleman than Cook, Cooper, Coleman, Knox and Kincaid. I think removing Knox for a WR, you lose the ability to be able to disguise the run. I love our offense in play action and RPO. Can't stand the shot gun sit back, with just 4 receiving targets running wherever.