Bernard will be out there and Miller is a role player at this point, so we'll likely be down 4 defensive starters along with Von and Austin Johnson.
The loss of Shakir will be huge as well. I'm willing to bet McD is being very conservative with some of these guys as we absolutely need to be closer to full strength for the key division game next week. It could very well get ugly again on defense. As someone else mentioned, I'm hoping for a Keon Coleman breakout game.