Indy is a solid team. Well coached, very good in the trenches. Taylor is a great RB, Hines is an excellent change of pace back. As far as how likely is it they win depends largely on which Wentz shows up. He can be solid or he can stink up the place.
I think the Bills will struggle a bit up front on offense. Daboll needs to get just enough out of the line to keep Josh under center as much as possible to open up the run game, roll outs and buy Josh more time.
All in all I can see this Colts team coming in and winning this game in a close one. However with NE winning last night Buffalo has to be feeling the pressure and I think they come out and do just enough to get the home victory
Bills: 27
Colts: 23