After hearing Patriots fans (mostly online) assume the bye week and likely homefield throughout for the past month+, it would be the most glorious day of my sports life to see the Bills come out from under the radar & take the division over this last month. Even today, if you go on the Pats boards or twitter, whenever you see the rare suggestion that the Pats could lose the division, it's met w/ a dozen or so replies along the lines of "to the Bills? Give me a break."
Ironically, the closest comparison would probably be something Boston fans experienced - going down by 3 games to the Yankees, a team that owned them for almost a century, and winning 4 in a row to improbably take that series and then go on to win the 'ship.
It would make the past 2 decades 100% worth it.