I think for the worst draft choices you can't just go by if they worked out or not and consider the information at the time of the choice. For that reason Maybin jumps out to me, he was known to have a small body and a poor choice when the Bills selected him. The Bills were fooled by some where he weighed 20 pounds more than he ever did before or since. People called it out right away as a poor choice mainly due to his size and all that became true. JP Losman was not a bad choice when the Bills selected him. Trent Edwards in the 3rd round, not a bad choice, he had a lengthy NFL career. Those guys did not become "franchise QB's" but at the time they were selected they were not bad choices.