For the NFL, the marquee matchups are often divisional based on rivalries. Having the home and away games are important and set up important "revenge games". I don't think you will get away from that. You could change up who is in what division but I dont think you are getting rid of the number of divisions. I think it is good how it is. But if you want to move the Pats to the NFC for the Cardinals, I would be for that.