I think the Bills should pretty much convert this draft into the #2 pick, and immediately start the QB selected. Deal whatever is needed to avoid giving up the 2019 first. Leave the team with many holes in important spots with and a rookie QB to struggle, post a poor record, and use the 2019 draft to shore up talent at the most needed positions, potentially with a blockbuster trade down of our own. From that point, we will ideally have an up-and-coming QB and a ton of cap space with some good young players to develop.
#21, #22, #53, #56, #65, Glenn, 2019 3rd, all for #2. Stay quiet in free agency this year, let young players start over veterans.