Now that Metcalf is officially listed as Doubtful...
Bills 27
Seahawks 13
I think the 1st half will be a bit of a defensive struggle. Mike Macdonald's simulated pressures could give our OL some trouble as we've seen a few times this year. The CBs they have are outstanding. Byron Murphy has been a force in the middle. For these reasons, plus a likely rainy day which Allen historically has struggled in, I don't expect a fast start on offense.
But on defense I really think we can shut them down. No Metcalf means we can cheat heavily towards stopping Kenneth Walker from taking over the game. The Seahawks are down to their 4th string RT - a 6th round rookie that played DII football - so Rousseau should have his way in this one. Geno Smith is basically an average QB so he isn't going to elevate his mediocre group of weapons and he will throw some interceptable passes. There is no reason we shouldn't dominate them defensively even with Bernard being out.
So I'll predict something like 13-13 at the end of the 3rd quarter, then in the 4th quarter we'll outscore them 14-0 to put the game away.