Leave your kid locked in a car for six hours? That's an arrestin. Lock your dog in a car for six hours? That's an arrestin. A bear was locked in your car for six hours? Look at the damage she caused!
https://www.wral.com/bear-trapped-inside-nc-family-s-suv-for-6-hours/20226325/
Could? Sure. Could a first or second round receiver/CB make immediate contributions? I trust Beane's band of merry men to pick the correct player in round 1 or 2 more than I trust them in later rounds.
The Bills have a strong roster, yes? They need players who can crack the roster, not be camp fodder. Trade up? For the right guy absolutely. Trade down for more/lower picks? Does not compute.