Moss. There are some good reasons not to trade Moss as other have mentioned. One reason to trade Moss is that he is likely inactive game days many weeks (assuming Cook pans out as expected). If Beane can get good value for Moss (5th round or higher draft choice), he might make that trade
If the Bills' front office likes Blackshear enough, they might try to trade Moss for some improved depth at OL or for future draft choice. I like Moss, but I don't think he will get much playing time behind Singletary and Cook.
Mix in some defensive sets using our depth at D-line and play 5 at a time bringing extra pressure up the middle. Also mix in corner/safety blitzes. Agree with others on not allowing Kelce a free release - need to impact the timing of his routes.