In my Humble Opinion.
Bills will obviously try to win from the get go:
QB - not gonna win games when losing in the 2nd half, but has ability to not lose you games if has lead in 2nd half.
RB - Above Average
WR - I have a dream...that Watkins lives up to his expectations..if not...Ouch
TE - Average.
O-Line - Average
Special Teams - Above average
Defense - Transition year but I believe they can be good and might re-ignite Jerry Hughes. Need Dareus to be mature ( highly doubt that will happen ) and the corners are young but full of piss and vinegar.
I don't see the Defense losing games.
I see nothing different from the last 17 years other than a coach that is young and new management.
So in Conclusion:
If they win from the get go, keep the run going and get that playoff. If they lose from the get go..sit Tyrod, give some reps to Ohio State boy and get a high draft pick. Use that high draft pick and the first rounder from KC and go get the best QB available.
Prediction: 9-7 Record if they start off good
3-13 record if they lose the first 2-3 games.
BTW: Losing Gilmore and Woods will make 0 impact on the outcome of this team.