I love playing with players that over value RB's.
My first three picks last year were Moss, Harrison and Vick. People thought I was crazy, my first RB was Lee Suggs in the 4th. The only other big picks I can remember was Bulger in 8th and the (awesome!!) Buffalo Bills defense
So both Vick and Suggs turned out to be busts. And then my biggest free agency pickups were Ashlie Lelie and Nick Goings.
Sounds like a good team right? (sarcasm on)
I very well should have won the league, but I ended up with only second place. I forget why but I lost the championship by sitting someone I should have started. My team was really good though. It was simply a bunch of dependable players that all got me 10 pts per week and it added up. No studs, no razzle dazzle, I even ended up trading away Vick for injured McNair.
There were some in my league that drafted RB's with the first 4 picks. They went nowhere since they had concentrated all of their talent into one area.
In other words, learn to balance the talent on your team and don't rely on just one player or position.