They are down their two biggest playmakers on D - Milano and White.
They don't have enough playmakers on O.
I don't think the team the Bills put on the field last night is good enough to win a Superbowl. The team that bashed Miami up? That team had a shot. But what has happened since starting with Tre's achillies at the end of that game has ended any title hopes this year.
That does NOT mean that everyone else, GM, coach, QB, players left gets a pass. They don't. But the Bills are not a Superbowl team this year. Can they scrape into the playoffs is the question.