First - Jethro Tull, War Child tour at the Niagara Falls Convention Center - I was 13. No idea who opened.
Favorite - Wow there are so many... In no particular order
Rush Presto tour - 2nd row center
Kiss at the Rochester War Memorial (1985 or so probably) - front row, elbows resting on stage
Van Halen Women & Children First tour 1981, Dallas
AC/DC Hells Bells tour 1981, Dallas
Live Throwing Copper tour, small club in Buffalo (Icon?) 1995 before the album hit big. Drummer threw sticks into crowd after show, one hit me in the bridge of the nose.