Walking out of Tampa Stadium after Super Bowl XXV, having to hear "New York, New York" as it was blaring out of the stadium speakers and seeing the celebrations of the Giants fans.
That was a very emotional day, with the Gulf War, the first ever Bills Super Bowl, the Whitney Houston Star-Spangled Banner, and the game itself. The only time I actually shed a tear over the Bills.
Against the Saints in San Antonio in their first "home" game after Hurricane Katrina.