I think the game was an anomaly and affected by so many variables that you really can't think it will be the norm for the Bills from here on out.
McD is a creature of structure and organization and the game plan got messed up by the uncertainty of the whole situation up to the game.
The players psyche was affected and never could get in the right frame of mind. Add in the injuries to key positions and the Bills were not mentally or physically at there best to play.
The Titans on the other hand were well rested and had 2 weeks to prepare for them. ( I know they had limited live practices but I am sure they had plenty of virtual practices) They also didn't have some of there starters as well but I don't think they equaled to our missing players. They also had a chip on their shoulders and were hugely motivated to play.
I would love for the game to be played again on more equal terms. The playoffs?