I'm pretty sure that the Patriots will not only win, but absolutely destroy our boys.
BUT...
We do have something going for us, and thats nobody expects us to win. If the Bills get creamed, which they probably will, people will just shrug their shoulders and say "Buffalo traveling to New England in the first game of the season? What did you expect to happen?".
That could work in the Bills' favor though.
No pressure to win. They're expected to lose. I know for a fact that players HATE playing teams like that because the pressure is squarely on their shoulders.
If the Bills lose...hey...thats what is supposed to happen. If the Patriots somehow lose though at home...whoo-boy, you'll see a lot of Pats fans running for the bridges in Boston.