If i'm calling the plays... I'm coming in heavy. Using a FB and TE on most snaps, and coming right at those linebackers. They're all solid, but they're all good coverage backers. Use the big boys up front and hammer them and make them a bit more miserable.
Then - Set up some play action, and attack their secondary. Even if its fake audibles to get them to cheat off the line, I want to dictate what they're doing.
I also practice a few plays in no-huddle, because this one could come down to a clutch halftime or game ending drive.