Lets say the Bills want to draft a QB at 10 they MIGHT find their guy at 10 but statistically speaking since 1999 the QBs taken at 10 or later haven't fared so well. Guys like Daunte Culpepper, Cade McNown, Matt Leinhart, Blaine Gabbert and Christian Ponder were all taken 10-12 or so. Only Big Ben, taken 11th in 2005 has been successful with Jay Cutler 11th in 2006 having moderate success a couple seasons.
Go back into the teens and it gets even worse. Kyle Boller at 19, Josh Freeman 17, EJ 16, Chad Pennington 18. Only Joe Flacco in 2008 at 18 has had moderate success. 20s, laughable besides Aaron Rodgers and to a much lesser extent Jason Campbell with guys like JP Loserman, Tim Tebow(ok he had the tebow factor but sucked), Rex Grossman, Brady Quinn and Johnny Manziel(ugh cleveland lol)
Heck even the very top of the draft is filled with duds, Akili Smith 3, Jamarcus Russel 1, Tim Couch 1(ugh Cle), Joey Harrington 3.
So if Trubisky is available at 10 is he a Roethlisberger or a Gabbert? One things for certain, Whaley and the scout team need to get it right.