Some good suggestions in this thread. I grew up with Talas, mentioned a little in this thread. Saw them many places, Barrelhead Tuesdays, He & She's, After Dark in Lockport. Billy was in Mr Big. Now lives in Nashville, among other things makes BBQ videos LOL. Fun fact, Billy crossed paths with Eddie Van Halen who hired him to be in VH replacing M Anthony. Billy accepted, but then never heard from Eddie again.
Some people here have to recall Kenny Wilczak, the literal Big man of Buffalo music maybe 50 years.
Here's a polarizing band suggestion, big in Buffalo like the last 25 years. Hit N Run. Imo, great classic rock, then wavered way too much in the genres they played. I lost interest