I sort of feel for Little in the same way that I feel for EJ.
Little is what this WR corps needs, and doesn't otherwise have. He's big, physical and fast and a decent route runner.
The problem is that he's just not a "natural" catcher of the football. If he were that he'd still be a Brown. You can clearly see that in his play. He has to do more to track and focus in on the ball than good WRs do, maybe not a whole lot more but at this level of competition it makes for a significant difference in the results. His hands are not NFL reliable.
EJ has all the physical tools you could want but he is just not a "natural" thrower of the football. A natural thrower either doesn't make the kinds of mistakes EJ does and which we sometimes describe as mechanical (I think they may be physiological at root) or overcomes them with coaching and training. EJ can and has improved but through no fault of his own he has a relatively low ceiling. Really its a shame but both Little and EJ would be well served by having less of what they bring to the table, which is a lot, and more of what they do not. Unfortunately you don't get to manage these things as you would like. I feel for both players. Close but definitely no cigar.
Little might make the cut and may actually be a contributor, but you can't count on it or him. Compare him with a guy like Powell. Different player types I realize, but Powell is definitely a natch. He just needs to refine his game so that he can continue to execute against starting calibre DBs and learn the friggen playbook.
How do you target a DB for punishment? If so inclined, and IMO Hall is, they get to ruin a WR's or even TE's career. If Hall sees Jason Peters or Earl Cambell coming at him at the second level I have no doubt he is a lot less aggressive, and maybe just gets out of the way. He is no Steve Atwater.