Yes, as mentioned by @Forward Progress
The sports Broadcasting Act of 1961 effectively outlaws NFL games on Friday or Saturday.
" It also, in effect, protects high school football and college football game attendance by blacking out pro football games locally on Friday evenings and Saturdays during those sports' regular seasons; these measures effectively outlawed the broadcasting (and, in practice, the playing) of NFL games on those days, since virtually all of the country is within 75 miles (120 km) of at least one high school game on every Friday night in September and October."
https://en.wikipedia.org/wiki/Sports_Broadcasting_Act_of_1961
https://uscode.house.gov/view.xhtml?path=/prelim@title15/chapter32&edition=prelim