Well, it doesn't need to be lightning quick and it's better if the drives take some time. After special teams, the biggest problem was the Bills unusual adherence to the running game that cost them downs and yards. Even if they were bringing the pressure, I would have preferred some short dump off plays. Sustain a couple of those drives, get better field position and let your defense rest a bit and while I don't think it would have been major, it would have made a difference for the defense.
This Bills team can't afford to have many 3 and outs. The defense is not what it was last year and even if they don't get points, they need to sustain drives on offense.