Nervous Guy

For you nature lovers out there...warning...a little "salty language".

Myth

bingo.

Hey...anybody see LGB or billsfreak today???

Seriously????? Pray tell. BTW...When "pray" was used to emphasize requests, this standard construction (as, "pray come here", "pray help us", "pray leave me") was an earnest request for information. The phrase is now, however, usually used ironically to emphasize the unacceptability of something, especially when highlighting a logical fallacy.

whoa...slow down there killa...joethesixpack "knows things".

ouch. hamstring...who knew???? DAMAGED GOODS

duh....he just "knows".

The Wonderlic test assesses the aptitude of prospective employees for learning and problem-solving in a range of occupations. Ya know that Marino scored a 16 and Fitz scored a 48? I also found this little tidbit...A study by Brian D. Lyons, Brian J. Hoffman, and John W. Michel found that Wonderlic test scores failed to positively and significantly predict future NFL performance for any position. The Lyons et al. (2009) study also found that the relationship between Wonderlic test scores and future NFL performance was negative for a few positions, indicating the higher a player scores on the Wonderlic test, the worse the player will perform in the NFL. Results from this study were recently highlighted in an Atlanta Journal-Constitution article by D. Orlando Ledbetter.

indeed...

added benefit...the new one will not sound like a jet engine...our new one is barely audible, while the old one was deafening! :thumbsup:

indeed...now all we have is that friggin' spice crap.

I'm specifically speaking about new projects that we work on...no more SSRI's, no mixed dopamine antagonists, etc...our given mandate is novel mechanisms,and trust me, it's tough business with unprecedented mechanisms, I can personally attest to the difficulty of doing this research. If the folks in formulation can improve the medication why not do it? That's not the me too's I was speaking about. and then the clinical trials take 4-5 more years....I don't know of many drugs that have been on the market for 17 years under patent protection. Maybe you can tell me a few.

If that would happen you can forget about any attempts to research and develop any new and innovative medications...what? then the academics could do it? Trust me, I've been doing R&D in the industry for more than 20 years, no way they could do it. We discard 100's if not 1000's of compounds before we advance 1, and that takes years. The hurdle is very high, you need new, unprecedented mechanisms, safety, great pharmacokinetics to advance a compound...maybe 10 years from synthesis to the clinic, then spend tens if not hundreds of millions to test it in humans...the days of "me too" medications were over years ago. Drug companies feel compelled to hit home runs now, not singles...shortening patent lives would lead to no new drugs...but yeah, everything would be cheap.

In the US, drug patents give twenty years of protection, but they are applied for way before any clinical trials begin, so the effective life of a drug patent tends to be between seven and twelve years. Are drug patents too short?

sorry Beerball..."twit war" is reserved for squabbles between you and DC Tom.

So Neuroscience is relocating to Cambridge MA in about 12-18 months...people will be identified in 6-8 weeks to be "invited" or "deselected"...me I'm in an interesting position they will give a generous severance (for me about 1 yrs. salary), plus they would give 5 years to either age or years of service...I've been here 20 yrs and am over 50...I could use that and do early retirement...total for me with severance and my pension...over 4yrs salary plus some health benefits...or maybe move at great financial peril to a job that might disappear in 2 years...hmmm....lots to think about. I've dodged at least 4 bullets here in the last 10 years...will the next one have my name on it? My son suggested to move to Buffalo.

so you can give advice but not receive it?

worth a try I guess.

It's every 10 years after the initial series.

WHAT?!?!?!?! In the corrupted currents of this word offence's gilded hand may solve by justice, and oft, tis seen the wicked prize itself buys out the law: but 'tis not so above; There is no shuffling, there the action lies in his true nature; And we ourselves.

Delusional disorder is classified as a psychotic disorder, a disorder where a person has trouble recognizing reality. Frequently the delusions involve circumstances that could occur in reality even though they are unlikely (for example, your phone calling itself). Themes of persecution are common (calls being tracked or bugged). This is interesting that you brought this to our attention since people with delusional disorder are aware that their beliefs are "unique" and they generally do not talk about them. Treatment for this disorder is challenging, especially if the delusion is long lasting. Antipsychotic medications can be helpful.

provided they all get boosters.