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Hapless Bills Fan

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Everything posted by Hapless Bills Fan

  1. I wonder if they know Haack has been hanging out with one of our Covidians
  2. The Bills mantra is "next man up", that they have "full confidence" in the other players and will rely on them to fill the same roles. I think that's BS and if the Bills rely on it, we're gonna lose. It seems to me it's going to take Daboll and his assistants crafting a game plan that caters to the strengths and weaknesses of the OL and the WR we have remaining on the field (I hope we have them remaining on the field) to get us through. Shingles says "Hi!" PS my parents didn't do that, and most of us can see a few differences between chicken pox and covid
  3. Yep. Also wondering if we might see Tanner Gentry or Isaiah Hodgins activated from the PS
  4. That was actually my thought when I read his "went home, took a nap, now I feel GREAT" tweet "guess you must have Delta" LOL
  5. Ha! No, that's just what I say when I read some of the stuff on here 😆
  6. I'm gonna respond to this, because I see a lot of people starting with our own Jon Feliciano on Twitter, sharing this belief and there's Need to Know. 1) Most of the monoclonal antibody therapies have greatly reduced effectiveness against Omicron. Monoclonal means "one clone" ie, a single antibody recognizing a specific amino acid binding site on the spike protein. The same mutations that make the antibodies raised by vaccines against the original strain less effective at preventing infection, greatly reduce effectiveness for the mAb therapies. 1000x for Regeneron (Casirivimab and Imdevimab). 3000x for Lilly (Bamlanivimab and Etesevimab). GSK Sotrovimab still works (only 2.7x lower) - for now. 2) The monoclonal antibodies are authorized for at risk patients, because they cost our government 100-500x as much as a vaccine ($2000/dose vs $4-20/dose), have much higher administration costs, and have limited supply. https://www.hhs.gov/guidance/document/monoclonal-antibody-covid-19-infusion As a "Big Guy", Dawkins and Lotulelei and Feliciano all qualify. Beasley and Davis should not, unless they secretly have Diabetes or take Immune-suppressive drugs. Think it's cool that elders and diabetics and immunosuppressed people might go without so athletes who don't wanna vaccinate can get them? I don't. 3) If a reason to not be vaccinated is concern for side effects, there should be awareness that the monoclonal antibody infusions have much higher prevalence of some nasty side effects. I don't want to "piss in my own pool", and this absolutely was my pool: If you need such drugs, by all means take them, they can be wonder drugs. The side effects are still rare, but they are much higher incidence than would ever be tolerated for any vaccine, anywhere.
  7. That's about where I am. I already shot down one of these damned threads this am. I shoulda left it up there shot full of bullet holes as a warning to the next ***** joker who forgets to put the humor in his "funnies" @Chandler#81 my sincere apologies for causing you trash to take out
  8. You really shoulda put a warning on that tweet. I just ate a pretty large birthday dinner and it made me nauseous
  9. I think it's more. If we're 91% vaccinated, (1-0.91) = 0.09; 0.09* (53+16) =6 Boettger (probably - refused to answer whether he's vaccinated pre-season); Brown; Lotulelei; Beasley; Davis That would be 4 out of 6 Klein may be another not vaccinated, although he came back in 9 days (but could have tested (+) the day before he was placed on the list, and been out 10) - he was sent home as a "close contact" along with Butler in the preseason. If so 5 out of 6 - so far https://www.sharpfootballanalysis.com/analysis/covid-19-list-tracker-for-players-nfl-policies/ So far 10 or 11 out of 63 vaccinated players That would be 16 or 17% of the vaccinated players and 67-83% of the unvaccinated players
  10. I agree with you about the "Witch hunt" atmosphere for unvaccinated players. The NFL did change their rules The problem is that you think you understand what the Covid situation is better than the NFL's medical experts do, and they didn't change their rules in the way you want. I posted the transcript of the press conference with Dr Allen Sills where he explains their rationale for changing the rules as they did. One may disagree, but the point is, he and the other advisors had specific scientific rationales for what they did. (in another thread) I'm very afraid of this. My understanding is that Diggs and Gabe Davis share the services of a personal chef outside the facility and sometimes eat dinner together.
  11. Adam Schefter tweeted no. He is an insider with agents. As far I know, Davis hasn't said - he did re-tweet some of Beasley's stuff
  12. For an unvaccinated player, I believe it is still a thing
  13. Yes, thank you - vaccinated close contacts don't need to quarantine, but they do need to test every day for 5 days
  14. https://www.buffalobills.com/news/bills-add-gabriel-davis-and-cody-ford-to-the-reserve-covid-19-list Star Lotulelei will miss a second practice for "Personal Reasons" - WTF?
  15. Do we know that for sure? What is the basis for this belief? If vaccinated, Davis would still be tested: 1) if chosen "randomly" by the testing company 2) if he had symptoms See above.
  16. Well, *****. I say this in the most friendly of Christmas Spirits: Go stick your head in a bowl.
  17. https://buffalonews.com/sports/bills/jim-kubiak-bills-qb-josh-allens-ball-skills-could-key-next-step-of-his-development/article_8ce541c0-61eb-11ec-a878-275f082fa019.html Kubiak grades each play on a "do your job" system (did Allen make a good throw/catchable ball or throw it away if no one open?) Interestingly, he graded Allen's 1st Q about the lowest of the season - 60% One has to wonder if Allen's foot affected his initial throws, and it took getting warmed up and perhaps getting his adrenaline going to settle in and be able to throw properly. But we can't afford a 1Q like that against the Pats. He has this to say about Allen's INT in an otherwise excellent 2Q: I had wondered from how far off the throw was, if Allen was expecting Diggs to run a different route option, but Kubiak feels Chinn made a good play and Allen passed up a safe throw to Knox, who would have been left open for lots o' yards. Live n Learn. That drop by Sweeney was bad. Gotta haul that in. Kubiak points out the critical role of the run game in helping to sell play-action and open up the passing game: Part of his conclusion:
  18. Burrows was born in Ames, Iowa and spent some time as a kid in Fargo, but he grew up and played HS ball in Athens, Ohio. Which still means Cincinnati as a bustling metropolis compared to where he's from Unless LSU has a ripping nightlife?
  19. Any port in a storm. I think the player we all hoped to get back also starts his last name with "D" but is shaped a bit different
  20. My screen name when I started posting here was "Hopeful" Through the hiring of Chan Gailey, Dave Wannstache as DC, Doug Marrone...I remained hopeful. I did not want Rex Ryan. I thought he was a bloviating gas bag. A fellow parent at my kid's school who is a HOF retired NFL player totally persuaded me of all the great things Ryan was going to do for the Bills. I'm sure this guy has forgotten more about football than I'll ever know, so I believed. The season starts. Patriots game. Undisciplined, unprepared, unfocused team. I knew right then what I was - a "Hapless Bills Fan"
  21. Hysterical Here's the actual Mic'd up https://www.buffalobills.com/video/mic-d-up-sean-mcdermott-x3384 Shows what's on his mind as stuff the team has to work on IMO.
  22. Doesn't the Hoodie make them sleep at a hotel the night before the game? I can't think he'd change just because of Christmas.
  23. Pretty good description of Paxlovid mechanism https://www.acsh.org/news/2021/11/16/pfizers-covid-drug-works-wonders-heres-how-it-works-15924 Bottom line up front: it's a protease inhibitor specific for the protease made by the Sars-Cov-2 virus, plus a second drug that extends the life of the protease inhibitor by blocking the human enzymes that degrade it. Heard of "protease inhibitor therapy" for HIV? Similar thing...the virus makes its proteins all in one long strand-o-beads that have to be cut in the correct location to be active and able to make a new virus. But the HIV protease uses a different mechanism, so its protease inhibitors didn't do too much for the Sars-Cov-2 protease inhibitor. The "business end" of a viral protease is a great target for pharmaceutical treatment because it can't mutate much (if at all), or the mutations put it "out of business". Omicron and its many mutations has only one mutation in the protease, and doesn't impact Paxlovid binding. For those who would like something meaty, here's the paper about it: https://www.science.org/doi/full/10.1126/science.abl4784# And if you're a drinkin' kind of guy, pour one and drink a toast to all the peons in R&D at Pfizer who have been working their donkeys off for the last 22 months to develop this molecule.
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