I don't think that we're doing a high powered/up tempo offense no matter who we have at QB. But I agree that if Tyrod winds up being the guy, and that he can be reasonably accurate, he absolutely can do well without needing pinpoint accuracy.
The Bills have playmakers who can do wonders with YAC on short passes (Sammy, Shady, Harvin, Clay) and guys who can truck it on the ground (Shady, Freddy, Karlos). Really, as long as you can make teams pay if they play too close by being able to hit a few deep passes you can run a working offense.