‘Key matchup: The Saints’ 13th-ranked running game, which averages about 118 yards per match, could have a productive day if DT Star Lotulelei misses a third game while on the Reserve/COVID-19 list. Buffalo allowed Colts RB Jonathan Taylor to score five times, including four times rushing. The Colts’ 264 yards rushing were the most Buffalo has allowed since giving up 298 in a 47-10 loss to New Orleans on Nov. 12, 2017. But New Orleans also has several injured running backs.’