‘According to Betonline.ag, the Bills open as a -17 favorite over the Houston Texans in their Week 4 game set for 1 p.m. next Sunday at Highmark Stadium. The last time the Bills were this large a favorite was in 2019 when they were -17 favorites against the Dolphins at home. Buffalo won that game, 31-21. They beat Miami, 37-20, on the road less than a month later to sweep the season series.’