‘For the past three seasons, Buffalo has played the Tennessee Titans in Week 5. This is just a coincidence by the schedule makers, but an odd one that went unnoticed on the calendar. Buffalo played host to Tennessee in Week 5 of the 2018 season then traveled to Nashville during the same week in 2019 and 2020. The Bills’ matchup against the Titans was in jeopardy last year after Tennessee had a COVID-19 breakout that altered its schedule, but the game ended up remaining in Week 5 and played on a Tuesday — the league’s first Tuesday game since 2010.’