‘The Bills remain relatively healthy going into today’s game, with only one player listed as OUT, safety Jaquon Johnson (ankle), and just one other listed as questionable, tight end Lee Smith (knee). Another player that Buffalo will be without this week is WR John Brown, who will miss his fourth straight game despite being designated to return from injured reserve and practicing this week. One factor that may have led the Bills’ decision to hold Brown back was that the Buffalo wideout has the sickle cell trait, which makes playing in locations with high altitudes, such as Denver, potentially dangerous.’