‘The Jaguars are a mediocre run defense, even with such a dominant front line that includes Marcell Dareus, Calais Campbell, and Malik Jackson, and playmaking linebackers like Paul Posluszny, Myles Jack, and Telvin Smith. Marcus Murphy and Mike Tolbert will probably share the rushing load, and it will be imperative for the Bills’ offensive line to get the job done because, unlike McCoy, neither of those two are going to be able to gain many yards on their own if the line breaks down.’