‘Can the red-zone defense stand tall? Saints quarterback Drew Brees is a future first-ballot Hall of Famer. It’s not realistic to say the Bills need to shut him down. The key for the Bills will be to limit the number of big plays against them, and also keep the Saints out of the end zone when they reach the end zone. Buffalo’s red-zone defense is 10th in the NFL, allowing touchdowns 50 percent of the time. The Saints, meanwhile, rank seventh in red-zone offense, scoring TDs 60 percent of the time.’