'This is a difficult game to predict. This will serve as the Broncos’ first road game of the 2017 season. Along with an injury to Broncos starting left tackle Garett Bolles, the Broncos offense may suffer from an inability to run the ball against the Bills’ defensive line. This could be a low-scoring affair if the Broncos do not get out to a fast start. In the end, the winner will be the team that can create scoring opportunities after turnovers, or the team who’s defense can score some points. Both defenses will confuse and frustrate these young quarterbacks. Look for the Broncos to eek out a win, 13-10.'