‘One of the biggest Week Six games in recent memory, the Bills have a tremendous opportunity to prove to the rest of the NFL that they are, in fact, for real as a genuine threat in the AFC playoff picture. Kyle Orton, Fred Jackson and company will have their opportunities on offense and they need to take advantage. The biggest difference between the teams in this game is how much of an advantage the Bills’ defensive line has over the interior of New England’s offensive line. That, combined with a charged up crowd at Ralph Wilson Stadium for the start of the Pegula era, could yield one of the biggest victories the Bills could attain in 2014.’